Table 2:
Brain regions with Brodmann areas (denoted in parenthesis) showing significant Group (healthy controls [C] vs. patients diagnosed with a psychotic spectrum disorder [P]) differences for micro- and macro-structural measures.
| Pattern 1: | GMC (BA) | MD (BA) | Viso (BA) | FA (BA) | Vic (BA) |
|---|---|---|---|---|---|
| Right IFG/Sylvian cistern | C>P (47) | ||||
| Left entorhinal | C>P (34) | ||||
| Right entorhinal | C>P (34) | ||||
| Left ventral entorhinal | C>P (20/28/36/38) | ||||
| Right ventral entorhinal | C>P (28/38) | ||||
| Left V2 | P>C (18) | ||||
| Thalamus | C>P (NA) | ||||
| Pattern 2: | |||||
| Left insula/VLPFC | C>P (13/44/45) | P>C (13/44/45) | C>P (13/44) | ||
| Left STG | C>P (22/42) | P>C (22) | |||
| Pattern 3 (GM): | |||||
| Left DLPFC | C>P (10/46) | ||||
| Right VLPFC | P>C (47) | C>P (44) | |||
| Right insula | P>C (13) | ||||
| Bilateral MPFC | P>C (9/10/11) | C>P (10) | |||
| Left IFG/Sylvian cistern | P>C (38) | ||||
| Right SFG/MFG | C>P (6/8) | ||||
| Left ACG | C>P (24/32) | ||||
| Midline middle/posterior CG | C>P (24) | ||||
| Left superior precentral gyri/CS | C>P (4/6) | ||||
| Left pre/postcentral gyri/CS | C>P (3/4/6) | ||||
| Right pre/postcentral gyri/CS/DLPFC | C>P (3/4/6/9) | ||||
| Right STG/MTG/ITG/LS | P>C (21/22) | C>P (21/22/39/42) | |||
| Pattern 3 (WM): | |||||
| Right cerebral and superior cerebellar peduncle | P>C (NA) | ||||
| Left SLF | C>P (NA) | C>P (NA) | |||
| Left CC | C>P (NA) | ||||
| Left anterior corona radiata | C>P (NA) | ||||
Notes: ACG = anterior cingulate gyrus; BA = Brodmann area; C = healthy controls; CC = corpus callosum; CG = cingulate gyrus; CS = central sulcus; DLPFC = dorsolateral prefrontal cortex; FA = fractional anisotropy; GMC = gray matter concentration; IFG = inferior frontal gyrus; ITG = inferior temporal gyrus; LS = lateral sulcus; MD = mean diffusivity; MFG = medial frontal gyrus; MPFC = medial prefrontal cortex; MTG = middle temporal gyrus; NA = Not Applicable; P = patients diagnosed with a psychotic spectrum disorder; SFG = superior frontal gyrus; SLF = superior longitudinal fasciculus; STG = superior temporal gyrus; Vic = intracellular neurite density volume fraction; Viso = free isotropic volume fraction; VLPFC = ventral lateral prefrontal cortex; V2 = secondary visual cortex.