Table 3:
Age at transplant | 71 | 70 | 65 | 67 | 54 |
Pre-transplant CKD | Yes | No | No | No | No |
Total bilirubin | 0.6 | 2.6 | 3.3 | 0.5 | 0.5 |
INR | 1.0 | 1.8 | 1.4 | 1.3 | 1.1 |
eGFR, mL/min/1.73m2 | 55 | 47.5 | 115 | 76 | 76.0 |
Diabetes | Yes | Yes | No | No | No |
Location | Home | Home | Home | Home | Home |
Etiology of liver disease | NASH | NASH | HCV | HBV | HBV |
Ventilated | No | No | No | No | No |
AFP at listing | 91 | 19 | 39 | 4 | 11 |
AFP at transplant | 224 | 20 | 11 | 7 | 14 |
Total tumor diameter at listing | 4.5 | 4.3 | 2.9 | 2.1 | 2.9 |
Total tumor diameter at transplant | 3.7 | 4.9 | 1.5 | 2.1 | 2.9 |
LiTES Score† | 14.2 | 19.7 | 27.9 | 38.2 | 52.7 |
Predicted post-transplant survival time based on LiTES | |||||
5-year time horizon | 4.07 | 4.17 | 4.34 | 4.50 | 4.66 |
10-year time horizon | 6.80 | 7.14 | 7.63 | 8.16 | 8.72 |
Abbreviations: eGFR=estimate glomerular filtration rate
Tumor size based on center to OPTN/UNOS and decreased sizes reflect changes from loco-regional therapy
LiTES score calculated based on coefficients from Table 1, with predicted survival time based on based on the survival curves developed in the validation cohort.