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. Author manuscript; available in PMC: 2021 Oct 15.
Published in final edited form as: Cancer Res. 2021 Feb 8;81(8):1942–1953. doi: 10.1158/0008-5472.CAN-20-2769

Figure 5. miR-31 differentially alters cellular signaling across histological subtypes of lung cancer.

Figure 5.

(A) Functional annotation of RNA-seq data for the most downregulated miR-31 predicted targets (B) Heatmap of Mean Kinase Statistic (MKS; log fold change in miR-31 overexpression from parent) values by cell line (H520 SQCC, H661 LCLC, H82 SCLC). (C, E, G) GSEA using MKS values. (D, F, H) Top altered kinases identified using whole-chip (all peptides) comparison for alteration between miR-31 overexpression and control. Blue: mean final score (MFS) Red: MKS