. 2020 Oct 5;60(4):2063–2075. doi: 10.1007/s00394-020-02396-w

Table 4.

Cardiovascular risk markers^a at baseline and after 9 and 18 weeks of intervention

	FO salmon (n = 17)	RO salmon (n = 17)	Control (n = 17)	p_treatment
Systolic blood pressure (mm Hg)
Baseline	131.2 ± 4.2	129.2 ± 3.5	133.4 ± 3.0	0.896
9 weeks	130.3 ± 3.5	125.4 ± 2.8	131.5 ± 3.1	0.296
18 weeks	129.3 ± 3.5	120.8 ± 3.1	129.5 ± 3.9	0.136
Diastolic blood pressure (mm Hg)
Baseline	80.7 ± 2.3	79.8 ± 1.7	78.1 ± 2.6	0.427
9 weeks	80.0 ± 1.9	80.2 ± 1.8	81.4 ± 2.1	0.275
18 weeks	77.9 ± 2.0	75.4 ± 2.1	77.8 ± 2.4	0.374
Heart rate (beats/min)
Baseline	64.4 ± 2.3	64.3 ± 2.0	63.2 ± 3.1	0.592
9 weeks	58.4 ± 2.2^a	63.9 ± 2.4^b	65.4 ± 3.3^b	0.002
18 weeks	61.9 ± 2.0	64.9 ± 2.8	65.0 ± 3.3	0.571
Total cholesterol (mmol/L)
Baseline	5.42 ± 0.30	5.49 ± 0.22	5.41 ± 0.28	0.864
9 weeks	5.66 ± 0.33	5.70 ± 0.22	5.54 ± 0.27	0.889
18 weeks	5.71 ± 0.28	5.46 ± 0.17	5.60 ± 0.27	0.123
HDL cholesterol (mmol/L)
Baseline	1.52 ± 0.08	1.74 ± 0.14	1.66 ± 0.11	0.251
9 weeks	1.68 ± 0.10	1.78 ± 0.13	1.74 ± 0.12	0.193
18 weeks	1.71 ± 0.11^a	1.73 ± 0.15^b	1.75 ± 0.11^a,b	0.012
LDL cholesterol (mmol/L)
Baseline	3.53 ± 0.26	3.33 ± 0.20	3.35 ± 0.22	0.781
9 weeks	3.53 ± 0.31	3.53 ± 0.24	3.43 ± 0.19	0.508
18 weeks	3.52 ± 0.24	3.29 ± 0.20	3.44 ± 0.21	0.393
Triglycerides (mmol/L)
Baseline	1.35 ± 0.18	1.26 ± 0.13	1.19 ± 0.12	0.660
9 weeks	1.19 ± 0.15	1.17 ± 0.11	1.19 ± 0.15	0.533
18 weeks	1.24 ± 0.21^a,b	1.08 ± 0.12^a	1.31 ± 0.16^b	0.050
Glucose (mmol/L)
Baseline	5.53 ± 0.12	5.67 ± 0.15	5.57 ± 0.12	0.599
9 weeks	5.73 ± 0.13	5.71 ± 0.22	5.62 ± 0.11	0.711
18 weeks	5.62 ± 0.10	5.65 ± 0.18	5.66 ± 0.11	0.804
Insulin (mU/L)
Baseline	7.71 ± 1.83	6.56 ± 0.95	6.13 ± 0.53	0.579
9 weeks	6.52 ± 0.68	6.45 ± 0.88	6.10 ± 0.64	0.717
18 weeks	6.86 ± 0.95	6.56 ± 0.80	6.37 ± 0.72	0.845
NEFA (mmol/L)
Baseline	0.44 ± 0.04	0.44 ± 0.05	0.53 ± 0.05	0.270
9 weeks	0.44 ± 0.05	0.45 ± 0.05	0.47 ± 0.06	0.455
18 weeks	0.54 ± 0.05	0.43 ± 0.03	0.45 ± 0.04	0.055
HOMA-IR
Baseline	1.95 ± 0.50	1.63 ± 0.21	1.53 ± 0.14	0.593
9 weeks	1.66 ± 0.17	1.65 ± 0.22	1.53 ± 0.17	0.638
18 weeks	1.66 ± 0.26	1.63 ± 0.19	1.62 ± 0.19	0.725
revQUICKI
Baseline	0.427 ± 0.016	0.421 ± 0.009	0.414 ± 0.010	0.684
9 weeks	0.430 ± 0.014	0.424 ± 0.011	0.437 ± 0.019	0.226
18 weeks	0.404 ± 0.010^a	0.421 ± 0.007^a,b	0.424 ± 0.011^b	0.041
Fibrinogen (g/L)
Baseline	2.86 ± 0.07	2.62 ± 0.05	2.60 ± 0.10	0.006
9 weeks	2.74 ± 0.09	2.72 ± 0.08	2.66 ± 0.11	0.267
18 weeks	2.73 ± 0.10	2.69 ± 0.08	2.58 ± 0.09	0.063
hs-CRP (mg/L)
Baseline	1.57 ± 0.69	1.68 ± 0.62	0.89 ± 0.27	0.036
9 weeks	2.89 ± 1.80	1.31 ± 0.63	1.36 ± 0.53	0.610
18 weeks	1.63 ± 0.87	1.31 ± 0.44	0.66 ± 0.26	0.596
s-ICAM (ng/mL)
Baseline	334.5 ± 16.0	311.2 ± 16.5	280.4 ± 7.6	0.024
9 weeks	325.3 ± 18.2	318.0 ± 14.0	279.5 ± 6.4	0.274
18 weeks	332.9 ± 20.6	308.3 ± 15.5	275.1 ± 7.9	0.760
p-Selectin (ng/mL)
Baseline	25.67 ± 2.37	25.77 ± 1.58	20.87 ± 1.17	0.100
9 weeks	24.53 ± 2.08	25.68 ± 1.57	20.95 ± 1.34	0.588
18 weeks	26.03 ± 2.21	25.03 ± 1.67	21.15 ± 1.20	0.741

^aAll values are mean ± SEM. p_treatment = p value for treatment effect between groups. Values with different superscript letters indicate that end values differ significantly (Tukey adjusted post hoc comparisons)