Table 4.
Patient groups (N = 517) | Total subjects for each patient group | Age: mean ± SD* | % of woman/men* | Number of medication; median ± IQR * | Total XI-scores: median ± IQR* | UWS: median ± IQR* | pH UWS: median ± IQR | CH-SWS: median ± IQR* | pH CH-SWS: median ± IQR | A-SWS: median ± IQR* | pH A-SWS: median ± IQR* |
---|---|---|---|---|---|---|---|---|---|---|---|
Controls | 136 | 50.6 ± 17.7 | 64.2: 35.8 | – | 27.0 ± 19.0–34.0 | 0.22 ± 0.07–0.36 | 6.50 ± 6.10–7.00 | 0.76 ± 0.44–1.33 | 7.00 ± 6.70–7.00 | 1.62 ± 1.01–2.20 | 4.70 ± 4.40–5.80 |
Low Med patients | 157 | 60.7 ± 14.8a | 68.2: 31.8 | 2 ± 1 – 2a | 30.0 ± 22.0–37.0a | 0.17 ± 0.07–0.32 | 6.50 ± 6.10–7.00 | 0.72 ± 0.39–1.18 | 7.00 ± 6.50–7.00 | 1.17 ± 0.71–1.80a | 4.70 ± 4.00–6.10 |
High Med patients | 140 | 65.9 ± 13.1a,b | 65.7: 34.3 | 6 ± 4 – 9a,b | 33.0 ± 24.0–40.0a,b | 0.11 ± 0.04–0.30a,b | 6.5− ± 5.80–6.90 | 0.57 ± 0.27–1.08a | 7.00–6.10-7.00 | 0.95 ± 0.44–1.50a,b | 4.40 ± 4.00–5.00a,b |
RTX patients | 10 | 58.7 ± 17.9 | 40.0: 60.0 | 1 ± 0 – 1a,b,c | 37.5 ± 31.0–43.8a,b | 0.13 ± 0.05–0.23 | 6.10 ± 5.65–6.90 | 0.45 ± 0.29–0.76 | 7.00 ± 6.40–7.00 | 0.52 ± 0.24–0.95a,b | 4.55 ± 4.15–5.08 |
SS patients | 46 | 61.7 ± 14.0a | 84.8: 15.2a,b,c,d | 2 ± −2a,b,c,d | 44.0 ± 37.0–49.8a,b,c | 0.08 ± 0.03–0.16a,b | 6.50 ± 6.00–6.80 | 0.30 ± 0.05–0.61a,b,c | 6.90 ± 6.10–7.00 | 0.50 ± 0.23–1.15a,b,c | 4.40 ± 4.00–5.00a,b |
SS + High Med patients | 22 | 62.1 ± 9.1a | 95.5: 4.5a,b,c,d | 7 ± 5 – 9a,b,d,e | 46.0 ± 37.5–49.5a,b,c,d | 0.06 ± 0.03–0.16a,b | 6.50 ± 5.50–7.00 | 0.28 ± 0.14–0.56a,b,c | 7.00 ± 6.50–7.00 | 0.48 ± 0.23–1.35a,b | 4.40 ± 4.00–4.70a,b |
Several patient characteristics for the six groups are shown; age, distribution of women and men in each group, the total number of medications used, the total XI-scores, salivary flow rates (in mL/min), and the salivary pH of UWS, CH-SWS, and A-SWS. The age is presented as mean with standard deviation (SD). For the number of medications used, the total XI-scores, salivary flow rates, and salivary pH, the median with corresponding interquartile range (IQR) is shown. The distribution of women and men is given in percentages
*Significant differences between the six patient groups, Kruskal-Wallis test p < 0.01
aMann-Whitney U test: p < 0.05 vs. controls
bMann-Whitney U test: p < 0.05 vs. Low Med patients
cMann-Whitney U test: p < 0.05 vs. High Med patients
dMann-Whitney U test: p < 0.05 vs. RTX patients
eMann-Whitney U test: p < 0.05 vs. SS patients