. 2021 Apr 22;56(6):489–526. doi: 10.1007/s00535-021-01784-1

Table 3.

Diagnostic criteria for ulcerative colitis [16]

Diagnostic criteria for ulcerative colitis
A. Clinical manifestations: persistent or recurrent mucous or bloody stools, or a history of them
B. Laboratory findings 1. Endoscopic examination a) The mucosa is diffusely affected, angiogenesis has disappeared, and the mucosa is coarse or granular. b) Multiple erosions, ulcers or pseudopolyposis are present. c) Basically, the lesion is continuous with the rectum 2. Ba enema a) Diffuse changes on the mucosal surface in the form of coarse or fine granules and b) multiple erosions, ulcers or pseudopolyps. Other findings include the loss of the haustra (lead tube) and the narrowing and shortening of the intestine
C. Histopathological findings: In the active phase, there is a diffuse inflammatory cell infiltration of all layers of the mucosa, crypt abscesses and a high degree of goblet cell depletion. All of these findings are nonspecific and should be judged in the aggregate. In remission, the glands remain misaligned (tortuous or branched) and atrophic. The above changes are usually seen from the rectum to the mouth in a continuous fashion

Diagnostic criteria for ulcerative colitis

A. Clinical manifestations: persistent or recurrent mucous or bloody stools, or a history of them

B. Laboratory findings

1. Endoscopic examination

a) The mucosa is diffusely affected, angiogenesis has disappeared, and the mucosa is coarse or granular. b) Multiple erosions, ulcers or pseudopolyposis are present. c) Basically, the lesion is continuous with the rectum

2. Ba enema

a) Diffuse changes on the mucosal surface in the form of coarse or fine granules and b) multiple erosions, ulcers or pseudopolyps. Other findings include the loss of the haustra (lead tube) and the narrowing and shortening of the intestine

C. Histopathological findings: In the active phase, there is a diffuse inflammatory cell infiltration of all layers of the mucosa, crypt abscesses and a high degree of goblet cell depletion. All of these findings are nonspecific and should be judged in the aggregate. In remission, the glands remain misaligned (tortuous or branched) and atrophic. The above changes are usually seen from the rectum to the mouth in a continuous fashion

Confirmed diagnosis of ulcerative colitis

(1) In addition to A, 1 or 2 of B and C are fulfilled

(2) 1 or 2 of B and C on more than one occasion

(3) Patients with gross and histological findings, which are characteristic of the disease on resection or autopsy