Table 2.
Effect of smoking history in all NSCLC and in adenocarcinoma ever smokers
| All NSCLC Ever Smokers (n=692) | Adenocarcinoma Ever Smokers (n=545) | |||||||
|---|---|---|---|---|---|---|---|---|
| Univariable Analysis | Multivariable Analysis | Univariable Analysis | Multivariable Analysis | |||||
| Parameters | Estimate (95% CI) | P | Estimate (95% CI) | P | Estimate (95% CI) | P | Estimate (95% CI) | P |
| Age | NA | NA | 1.00 (1.00–1.01) | 0.10 | NA | NA | 1.00 (1.00–1.01) | 0.02 |
| Male vs female | NA | NA | 0.95 (0.85–1.05) | 0.30 | NA | NA | 0.91 (0.81–1.03) | 0.15 |
| Squamous cell Carcinoma vs Adenocarcinoma | NA | NA | 1.2 (0.97–1.49) | 0.09 | NA | NA | NA | NA |
| Others vs adenocarcinoma | NA | NA | 1.1 (0.94–1.27) | 0.23 | NA | NA | NA | NA |
| Stage IV vs III | NA | NA | 0.93 (0.84–1.04) | 0.22 | NA | NA | 0.90 (0.79–1.02) | 0.10 |
| Doubling Smoking pack-years | 1.16 (1.10–1.23) | <0.001 | 1.14 (1.08–1.21) | <0.001 | 1.13 (1.07–1.19) | <0.001 | 1.11 (1.04–1.24) | <0.001 |
| Doubling Smoking-free months | 0.97 (0.95–0.98) | <0.001 | 0.96 (0.94–0.98) | <0.001 | 0.97 (0.95–0.99) | <0.001 | 0.95 (0.92–0.99) | <0.001 |
*
Only the statistically significant slopes for smoking pack-years are presented in the table.