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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Circ Arrhythm Electrophysiol. 2021 Apr 9;14(5):e009393. doi: 10.1161/CIRCEP.120.009393

Table 1.

Pre-Mortem Conditions for WHO-Defined (Presumed) SCDs by Sex and Race.

WHO-Defined (Presumed) SCDs (525)

Sex Race

 No. (%) Female Male p* Asian p* Black p* Hispanic p* White

163 (31) 362 (69) 110 (21) 81 (15) 40 (8) 279 (53)
Medical Records Unobtainable 8 (5) 25 (7) NS 8 (7) NS 5 (6) NS 2 (5) NS 18 (6)
Confirmed No Medical History 8 (5) 16 (4) NS 9 (8) NS 2 (2) NS 3 (8) NS 10 (4)
Age (years) 66.9 ± 15.1 60.9 ± 13.8 <0.01 67.3 ± 15.1 <0.01 60.3 ± 14.5 NS 59.3 ± 16.2 NS 62.3 ± 13.7
History of:
 Hypertension 100 (61) 190 (53) NS 64 (58) NS 57 (70) <0.01 21 (53) NS 138 (49)
 Diabetes Mellitus 42 (26) 75 (21) NS 33 (30) <0.01 22 (27) <0.05 13 (33) <0.01 44 (16)
 Dyslipidemia 50 (31) 107 (30) NS 43 (39) <0.05 23 (28) NS 9 (23) NS 79 (28)
 Myocardial Infarction 25 (15) 51 (14) NS 11 (10) NS 16 (20) NS 8 (20) NS 38 (14)
 Congestive Heart Failure 20 (12) 48 (13) NS 13 (12) NS 18 (22) <0.01 4 (10) NS 30 (11)
 Chronic Kidney Disease (non-ESRD) 24 (15) 34 (9) NS 12 (11) NS 21 (26) <0.01 4 (10) NS 18 (6)
 Seizure Disorder 13 (8) 26 (7) NS 2 (1) <0.05 8 (10) NS 6 (15) NS 21 (8)
 Cerebrovascular Accident 17 (10) 16 (4) <0.01 10 (9) <0.05 8 (10) 0.01 4 (10) <0.05 9 (3)
 Psychiatric Disorder 58 (36) 85 (23) <0.01 16 (15) <0.01 30 (37) NS 11 (28) NS 83 (30)
Chronic Obstructive Pulmonary Disease 27 (17) 37 (10) <0.05 13 (12) NS 15 (19) NS 5 (13) NS 31 (11)
 Non-Metastatic Cancer 23 (14) 40 (11) NS 7 (6) <0.05 11 (14) NS 3 (8) NS 42 (15)
 Tobacco Use 54 (33) 157 (43) <0.05 31 (28) <0.01 37 (46) NS 20 (50) NS 119 (43)
 Excess Alcohol Use 16 (10) 106 (30) <0.01 11 (10) <0.01 21 (26) NS 14 (35) NS 74 (27)
 Illicit Drug Use 21 (13) 58 (16) NS 1 (1) <0.01 26 (32) <0.01 9 (23) NS 43 (15)

ESRD indicates end-stage renal disease; SCD, sudden cardiac death

*

p-value comparing Female vs. Male and comparing Asian, Black, and Hispanic vs. White

Includes prior diagnosis of Depression, Anxiety, Schizophrenia, Bipolar Disorder, PTSD, Mood Disorders, Psychosis, Borderline Personality Disorder, Obsessive Compulsive Disorder, Insomnia, and other psychiatric conditions not otherwise specified