Table 4.
Pre-Mortem Conditions in Autopsy-Defined SADs by Sex and Race.
| Autopsy-Defined SAD (293) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Sex | Race | |||||||||
| No. (%) | Female | Male | p* | Asian | p* | Black | p* | Hispanic | p* | White |
| 73 (25) | 220 (75) | – | 68 (23) | – | 35 (12) | – | 21 (7) | – | 160 (55) | |
| Medical Records Unobtainable | 2 (3) | 13 (6) | NS | 5 (7) | NS | 2 (6) | NS | 2 (10) | NS | 6 (4) |
| Confirmed No Medical History | 5 (7) | 10 (5) | NS | 6 (9) | NS | 1 (3) | NS | 0 (0) | NS | 8 (5) |
| Age (years) | 70.6 ± 13.4 | 61.7 ± 14.4 | <0.01 | 66.5 ± 16.0 | NS | 61.0 ± 16.8 | NS | 60.6 ± 18.8 | NS | 64.3 ± 12.7 |
| Female | – | – | – | 21 (31) | 0.04 | 13 (37) | 0.02 | 6 (29) | NS | 30 (19) |
| History of: | ||||||||||
| Hypertension | 46 (63) | 129 (59) | NS | 40 (59) | NS | 25 (71) | NS | 11 (52) | NS | 94 (59) |
| Diabetes Mellitus | 21 (29) | 51 (23) | NS | 19 (28) | NS | 10 (29) | NS | 9 (43) | 0.01 | 31 (19) |
| Dyslipidemia | 23 (32) | 85 (39) | NS | 29 (43) | NS | 13 (37) | NS | 6 (29) | NS | 58 (36) |
| Myocardial Infarction | 12 (16) | 37 (17) | NS | 6 (9) | NS | 9 (26) | NS | 5 (24) | NS | 27 (17) |
| Congestive Heart Failure | 11 (15) | 36 (16) | NS | 8 (12) | NS | 11 (31) | 0.02 | 3 (14) | NS | 23 (14) |
| Chronic Kidney Disease (non ESRD) | 11 (15) | 22 (10) | NS | 6 (9) | NS | 11 (31) | <0.01 | 3 (14) | NS | 11 (7) |
| Seizure Disorder | 3 (4) | 11 (5) | NS | 2 (3) | NS | 2 (6) | NS | 2 (10) | NS | 7 (4) |
| Cerebrovascular accident | 8 (11) | 10 (5) | <0.05 | 5 (7) | NS | 5 (14) | <0.01 | 2 (10) | NS | 5 (3) |
| Psychiatric Disorder† | 19 (26) | 42 (19) | NS | 9 (13) | NS | 10 (29) | NS | 5 (24) | NS | 37 (23) |
| Chronic Obstructive Pulmonary Disease | 11 (15) | 21 (10) | NS | 7 (10) | NS | 5 (14) | NS | 3 (14) | NS | 17 (11) |
| Non-Metastatic Cancer | 15 (21) | 25 (11) | <0.05 | 6 (9) | NS | 6 (17) | NS | 2 (10) | NS | 26 (16) |
| Tobacco Use | 19 (26) | 96 (44) | <0.01 | 19 (28) | <0.05 | 14 (40) | NS | 12 (57) | NS | 67 (42) |
| Excess Alcohol Use | 2 (3) | 55 (25) | <0.01 | 7 (10) | 0.03 | 6 (17) | NS | 6 (29) | NS | 36 (23) |
| Illicit Drug Use | 1 (1) | 26 (12) | <0.01 | 1 (1) | 0.02 | 8 (23) | 0.04 | 2 (10) | NS | 16 (10) |
ESRD indicates end-stage renal disease; SAD, sudden arrhythmic death
*
p-value Female vs. Male, and Asian, Black, and Hispanic vs. White
†
Includes prior diagnosis of Depression, Anxiety, Schizophrenia, Bipolar Disorder, PTSD, Mood Disorders, Psychosis, Borderline Personality Disorder, Obsessive Compulsive Disorder, Insomnia, and other psychiatric condition not otherwise specified