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. 2021 May 7;13:668775. doi: 10.3389/fnagi.2021.668775

TABLE 1.

The effects of AP-32, RM, and A-RM on serum biochemical profiles after 8 weeks of treatment in 6-OHDA-induced PD rats.

Biochemistry levels NC PD L AP-32 RM A-RM
TCHO (mg/dL) 81.8 ± 21.2 84.4 ± 14.7 75.8 ± 13.6 85 ± 17.5 71.7 ± 11.1 77.3 ± 11.1
TG (mg/dL) 108.8 ± 46.7 94 ± 44.7 96.8 ± 46.2 104.7 ± 25.6 107.7 ± 14.9 95.0 ± 56.4
HDL (mg/dL) 44.8 ± 9.6 46.7 ± 15.0 46.8 ± 6.3 39.2 ± 6.0 39.7 ± 11.1 33.3 ± 3.8
AST (u/L) 183.3 ± 54.5 247 ± 55.3 185 ± 52.0 141.3.8 ± 31.1 274.3 ± 50.5 318.0 ± 50.8
ALT (u/L) 47.8 ± 4.1 54.3 ± 8.0 43.5 ± 5.2 43 ± 3.7 46.7 ± 5.3 59.3 ± 9.9
ALB (g/dL) 4.6 ± 0.9 3.7 ± 0.2 4.3 ± 0.7 3.9 ± 0.4 3.5 ± 0.1 3.8 ± 0.2
TP (g/dL) 7.2 ± 0.8 6.4 ± 0.3 6.8 ± 0.6 6.4 ± 0.3 6.1 ± 0.2 6.4 ± 0.2

All data are expressed mean ± SEM (n = 5 rats/group). There is no significant difference between groups. NC, normal control; PD, untreated PD as negative control; L, PD treated with 8 mg of L-DOPA as a positive control; AP-32, PD treated with 1.03 × 109 CFU/kg BW of AP-32; RM, PD treated with 62 mg/kgBW of residues of microbial culture medium RM; A-RM, PD treated with AP-32 and 62 mg/kgBW of residues of microbial culture medium RM. TCHO, Total Cholesterol; TG, Triglycerides; HDL, High Density Lipoprotein-Cholesterol; AST, Aspartate Aminotransferase; ALT, Alanine Aminotransferase; ALB, Albumin; TP, Total Protein.