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. 2021 May 7;13:668775. doi: 10.3389/fnagi.2021.668775

TABLE 4.

The effect of AP-32, RM, and A-RM on fecal SCFAs profiles after 8 weeks of treatments.

SCFAs (mM) NC PD L AP-32 RM A-RM
Total acid 6.43 ± 0.64 4.48 ± 1.37# 5.38 ± 1.28 6.39 ± 0.42* 6.42 ± 0.87* 6.50 ± 1.73*
Acetic acid 4.33 ± 0.61 3.63 ± 1.36 3.99 ± 0.92 4.49 ± 0.53 4.96 ± 0.79 4.92 ± 0.90
Propionic acid 1.06 ± 0.06 0.58 ± 0.16# 0.95 ± 0.12* 0.93 ± 0.10* 1.00 ± 0.07* 1.16 ± 0.37*
Isobutyric acid 0.03 ± 0.01 0.03 ± 0.00 0.03 ± 0.01 0.05 ± 0.01* 0.04 ± 0.02 0.04 ± 0.01
Butyric acid 1.80 ± 0.13 0.54 ± 0.11# 0.90 ± 0.38 1.57 ± 0.38* 1.23 ± 0.21* 1.21 ± 0.61*
Isovaleric acid 0.02 ± 0.00 0.01 ± 0.00 0.01 ± 0.01 0.03 ± 0.01* 0.03 ± 0.01* 0.02 ± 0.00
Valeric acid 0.08 ± 0.01 0.06 ± 0.01 0.05 ± 0.01 0.07 ± 0.02 0.05 ± 0.03 0.05 ± 0.02

Data are expressed as mean ± SEM (n = 5 rats/group). #p < 0.05 PD group compared to NC group. *p < 0.05 L, AP-32, RM, and A-RM groups compared to PD group. There is no significant difference between AP-32, RM, and A-RM. One-way ANOVA with Tukey’s post hoc test. SCFAs, short-chain fatty acids.