Figure 4.

Log reduction of P. aeruginosa Xen41 biofilms, after being grown for 3 d in TSB media and then introduced into the large plate model against one of three antibiotic conditions for 5 d. CFU counts of SS-316 (a), Ti (b), HA (c), and UHMWPE (d) from the biofilm-colonized discs, varying in distance from the edge of the PMMA spacer, were compared to those on an unloaded spacer (US) control. $\ge$ denotes discs eradicated of biofilm bacteria to below the CFU detection limit (3.54 log${}_{\mathrm{10}}$ CFU/cm${}^{\mathrm{2}}$) and indicates that the reduction could be greater than or equal to the value listed in the graph. * represents statistically significant ($p<\mathrm{0.05}$) differences in log reductions between LS and LS $+$ ALCS-B antibiotic conditions.