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. 2021 May 7;11:657506. doi: 10.3389/fonc.2021.657506

Table 1.

Relationship between non-predominant micropapillary pattern and clinic-pathological variables before and after PSM.

Variables Before matching (n = 866) P value After matching (n = 460) P value
M+ not pren = 344 M−n = 522 M+ not pren = 230 M−n = 230
Age
 ≤60 173 283 116 127
 >60 171 239 0.258 114 103 0.304
Sex
 Male 151 225 105 87
 Female 193 297 0.818 125 143 0.089
Smoking status
 Yes 148 220 100 94
 No 196 302 0.798 130 136 0.571
Tumor laterality
 Left 148 173 84 90
 Right 196 349 0.003 146 140 0.564
Papillary subtype
 P− 276 385 183 172
 P+ not pre 37 98 33 41
 P pre 31 39 0.006 14 17 0.473
Solid subtype
 S− 261 339 187 180
 S+ not pre 38 67 28 29
 S pre 23 72 0.001 15 21 0.562
Spread through air spaces
 Yes 97 102 53 60
 No 247 420 0.003 177 170 0.448
Lymphovascular invasion
 Yes 55 86 39 28
 No 289 436 0.849 191 202 0.146
CEA (ug/L)
 ≤5 223 406 171 177
 >5 114 105 <0.001 59 53 0.515
Tumor size (cm)
 ≤1 23 64 16 17
 >1 to ≤2 148 244 99 93
 >2 to ≤3 173 214 0.004 115 120 0.850
Lymph node metastasis
 Yes 128 106 62 59
 No 216 416 <0.001 168 171 0.751
Pathological stage
 I 216 415 168 171
 II 22 29 13 10
 IIIA 106 78 <0.001 49 49 0.811

M−, micropapillary <5%; M+ not pre, micropapillary ≥5%, but not predominant; M pre, micropapillary predominant;

S−, solid <5%; S+ not pre, solid ≥5%, but not predominant; S pre, solid predominant;

P−, papillary <5%; P+ not pre, papillary ≥5%, but not predominant; P pre, papillary predominant;

PSM, propensity score matching.