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Post-infusion serum concentrations.
| ADC (N = 12) | TA (N = 163) | MMAE (N = 48) | |
|---|---|---|---|
| Mean ± SD (range) μg/ml | Mean ± SD (range) μg/ml | Mean ± SD (range) ng/ml | |
| Cycle 1 | 58.6 ± 15.5 (38.8–98.3) | 49.4 ± 16.5 (21.4–127.4) | 1.52 ± 1.10 (0.36–5.02) |
| Cycle 2 | 56.1 ± 11.0 (45.3–85.6) | 47.3 ± 15.0 (11.8–89.9) | 1.40 ± 0.83 (0.042–4.26) |
ADC antibody–drug conjugate, TA total antibody, MMAE monomethyl auristatin E, SD standard deviation.
