Table 1.

Antibody ID and working dilutions.

Antibodies	Supplier	Cat. no.	Working dilution, application
Anti-P-ERK1/2	Cell Signaling Technology	Cat.# 9101	1:1000 WB
Anti-ERK1/2	Cell Signaling Technology	Cat. # 4695	1:1000 WB
Anti-GPR116	Abcam	Cat.# ab136262	1:1000 WB
Anti-GPR116	Abcam	Cat.# ab111169	1:1000 WB 0.4 μg/ml as a blocking antibody in vitro
Anti-FNDC4	Sigma Aldrich	Cat. # SAB1401807	1:1000 WB
Anti-beta tubulin	Sigma Aldrich	Cat. # T5201	1:1000 WB
Anti-VCP	Abcam	Cat. # ab109240	1:1000 WB
Monoclonal ANTI-FLAG® M2-Peroxidase (HRP)	Sigma Aldrich	Cat. # A8592	1:1000 WB
Anti-rabbit, HRP conjugated	DAKO	Cat.# P0399	1:10,000 WB
Anti-mouse IgG-HRP conjugated	DAKO	Cat.# P0447	1:10,000 WB
Anti-F(ab’)2-goat anti-human IgG Fc secondary antibody, PE	Invitrogen	Cat.# H10104	1:200 FACS
Anti- Cd68	Abcam	Cat.# ab125212	1:500 IHC
Anti-beta actin	Sigma Aldrich	Cat.# A5441	1:1000 WB
Anti-pAS160(Thr642)	Cell Signaling Technology	Cat.# 4288	1:1000 WB
Anti-AS160	Cell Signaling Technology	Cat.# 2670S	1:1000 WB
Anti-pAKT(Ser473)	Cell Signaling Technology	Cat.# 9271S	1:1000 WB
Anti-AKT	Cell Signaling Technology	Cat.# 9272	1:1000 WB
Anti-phopho-PKA substrate	Cell Signaling Technology	Cat.# 9624	1:1000 WB
Anti-pCREB(Ser133)	Cell Signaling Technology	Cat.# 9198	1:1000 WB
Anti-pAMPKa(Thr172)	Cell Signaling Technology	Cat.# 2535	1:1000 WB
Anti-HO-1	Cell Signaling Technology	Cat.# 43966	1:1000 WB
Anti-pSTAT3(Tyr705)	Cell Signaling Technology	Cat.# 9145	1:1000 WB
Anti-STAT3	Cell Signaling Technology	Cat.# 12640	1:1000 WB
Anti-phopsho-PKC substrate	Cell Signaling Technology	Cat.# 6967	1:1000 WB
Secondary antibody: goat anti rabbit-biotinylated	Vector	BA-1000	1:750 IHC
Rabbit IgG, polyclonal—isotype control (ChIP grade)	Abcam	Cat.# 171870	0.4 μg/ml as a blocking antibody in vitro