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. 2021 May 7;15:657507. doi: 10.3389/fnins.2021.657507

FIGURE 2.

FIGURE 2

The effects of EA on depressive and anxiety-like behaviors induced by CCI rats. The anxiety-like behavior was accessed by both in the open field test (OFT) (A–D) and elevated plus maze test (EPMT) (E,F). (A) Distance in center of the OFT; (B) time spent in center of the OFT; (C) entries in center of the OFT; (D) total distance in the OFT; (E) distance in the open arms of the EPMT; (F) time spent in the open arms of the EPMT; (G) the frequency number of head dips (EPMT). The depressive-like behavior was in the forced swimming test (FST) (H). All data are expressed as the mean ± SEM (n = 13 per group). *p < 0.05, **p < 0.01, ***p < 0.001 vs. the sham group; #p < 0.05, ##p < 0.01, ###p < 0.001 vs. the CCI group. The “n.s” means no statistical differences were observed among three groups.