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. 2021 May 20;11:10658. doi: 10.1038/s41598-021-90125-6

Table 2.

Association of frailty transitions and cognitive function.

Variables Cognitive function (K-MMSE)
Men Women
ß SE P-value ß SE P-value
Frailty transitions
Non-frail → non-frail Ref. Ref.
Frail → non-frail − 0.628 0.254 0.013 − 0.276 0.217 0.203
Non-frail → frail − 1.635 0.222 < 0.0001 − 1.799 0.215 < 0.0001
Frail → frail − 1.879 0.252 < 0.0001 − 1.651 0.216 < 0.0001
Age
65–74 Ref. Ref.
75–84 − 0.298 0.103 0.004 − 0.545 0.110 < 0.0001
85 ≤  − 0.789 0.230 0.001 − 1.449 0.243 < 0.0001
Education level
Lower than middle school − 0.769 0.152 < 0.0001 − 1.121 0.192 < 0.0001
Middle school graduate − 0.480 0.164 0.003 − 0.569 0.229 0.013
High School graduate − 0.351 0.141 0.013 − 0.782 0.250 0.002
University graduate Ref. Ref.
Income level
Low 0.253 0.189 0.181 − 0.173 0.193 0.370
Middle low 0.350 0.190 0.066 0.081 0.200 0.688
Middle high 0.389 0.201 0.053 − 0.009 0.221 0.966
High Ref. Ref.
Marital status
Married Ref. Ref.
Unmarried − 0.126 0.174 0.470 − 0.161 0.110 0.145
Economic activity
Active Ref. Ref.
Inactive − 0.564 0.114 < 0.0001 − 0.306 0.149 0.040
Region
Urban 0.237 0.122 0.052 0.431 0.124 0.001
Rural Ref. Ref.
Smoking
Current 0.060 0.144 0.676 − 0.456 0.477 0.339
Past − 0.063 0.119 0.596 0.058 0.268 0.828
Never Ref. Ref.
Drinking
Current 0.015 0.129 0.905 0.178 0.156 0.253
Past − 0.160 0.150 0.287 − 0.415 0.228 0.069
Never Ref. Ref.
BMI
Overweight − 0.086 0.133 0.516 0.406 0.124 0.001
Normal Ref. Ref.
Underweight 0.252 0.222 0.256 − 0.194 0.251 0.441
Regular physical activity
Yes Ref. Ref.
No − 0.459 0.107 < 0.0001 − 0.474 0.124 0.000
ADL limitations
Yes − 3.896 0.708 < 0.0001 0.167 0.481 0.729
No Ref. Ref.
IADL limitations
Yes − 0.670 0.195 0.001 − 1.617 0.249 < 0.0001
No Ref. Ref.
Number of chronic diseases
0 Ref. Ref.
1 0.256 0.110 0.019 − 0.208 0.128 0.104
≥ 2 − 0.005 0.133 0.969 − 0.385 0.151 0.011
Lagged dependent variable
MMSE score of prior year 0.600 0.018 < 0.0001 0.665 0.014 < 0.0001

K-MMSE Korean-Mini Mental Status Evaluation, β regression coefficient, SE standard error.