Table 2.
Resuscitation outcome.
| Control n = 8 |
Esmolol n = 8 |
p value | |
|---|---|---|---|
| Defibrillations to ROSC, n | 2 [1, 2] | 1 [1–1.5] | 0.43 |
| Recurrent VFs within 15 min post ROSC, n | 7 [0.5–19.5] | 0 [0–9] | 0.29 |
| Duration of CPR prior to ROSC, sec | 320 [300–62] | 304 [301.5–307] | 0.88 |
| Total defibrillations delivered to final resuscitation, n | 8 [2–29] | 7 [1–12] | 0.28 |
| Successful resuscitation, n | 7/8 | 7/8 | > 0.99 |
| 96 h survival, n | 4/7 | 4/7 | > 0.99 |
| 96 h survival with good OPC score, n | 2/7 | 3/7 | > 0.99 |
| NAS | |||
| 24 h | 63 [38–88] | 63 [21–100] | > 0.99 |
| 48 h | 76 [50–100] | 70 [30–100] | 0.60 |
| 72 h | 76 [53–96] | 100 [40–100] | 0.90 |
| NDS | |||
| 24 h | 116 ± 38 | 119 ± 53 | 0.97 |
| 48 h | 65 ± 18 | 103 ± 50 | 0.56 |
| 72 h | 60 ± 35 | 79 ± 56 | 0.79 |
Data are expressed as median and interquartile range or mean ± SEM.
ROSC, return to spontaneous circulation; CPR, cardiopulmonary resuscitation; OPC, Overall performance category (OPC was defined good when = 1–2); NAS, Neurological Alertness Score; NDS, Neuronal Deficit Score.