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. 2021 May 7;9:665813. doi: 10.3389/fcell.2021.665813

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Copyright © 2021 Tang, Liu, Liu, Yu, Wang, Tan and Ye.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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New bone formation within bone tunnel. (A) Representative radiographs at 4, 8, and 12 weeks after surgery. (B) Representative 3D micro-CT images within a region of interest of central 2.5 mm in diameter of the bone tunnel at 4, 8, and 12 weeks after surgery. (C) Quantitative analysis of micro-CT of the new bone in the bone tunnel at 4, 8, and 12 weeks after surgery: (C1) BV; (C2) BV/TV; (C3) Tb.N; (C4) BMD; (C5) Tb. Sp. n = 8. *p < 0.05 vs. control group, **p < 0.01 vs. control group, ***p < 0.001 vs. control group, ^#p < 0.05 vs. PT group, ^##p < 0.01 vs. PT group. Reproduced from Lai et al. (2019) with permission from Elsevier (Copyright 2019).