Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 7;8:660072. doi: 10.3389/fmolb.2021.660072

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Chang, Guan, Wang, Chen, Zhu, Wei and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Knockdown of Cox4i2 suppresses HHV7-induced RSC96 cell apoptosis via ERK signalling pathway. (A) The apoptotic cells appear green, and the DAPI staining for the nuclei is blue. Representative TUNEL staining image of a mouse section and the percentage of TUNEL positive cells. (B,C) Protein and relative mRNA expressions of caspase3 were analysed by Western Blotting and RT-qPCR in vivo. (D) Representative TUNEL staining image of HHV7-infected RSC96 cells with or without shCox4i2 and the percentage of TUNEL positive cells. (E) Relative mRNA expression of caspase3 was analysed by RT-qPCR in RSC96 cells. (F) Protein expressions of pERK, ERK, and caspase3 were analysed by Western Blotting in RSC96 cells. Data are presented as the mean ± standard deviation, n = 3. Statistical significance was assessed with Student’s t-test and one-way ANOVA. **P < 0.01.