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. 2021 May 7;12:641491. doi: 10.3389/fpsyt.2021.641491

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Copyright © 2021 Ye, Wang, Zhu, Wang, Li, Tang and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Taxonomic differences in fecal microbiota between HCs and MDD patients. Comparison of relative abundance at the bacterial phylum (A), family (B) and genus (C) levels between HCs and MDD patients. LEfSe identified the most differentially abundant taxa between HCs and MDD patients. The brightness of each dot is proportional to its effect size (D). Taxa enriched in HCs are indicated with a negative logarithmic discriminant analysis (LDA) score (red), and taxa enriched in MDD patients have a positive score (green). Only taxa meeting an LDA significance threshold > 3.5 are shown (E).