Table 3.
Association between baseline patient characteristics and longitudinal change in SF-36 measurements over one year.
| Female | Age at baseline (10 year increase) | Disease duration at baseline (10 year increase) | EDSS score at baseline | Progressive disease category at baseline | |
|---|---|---|---|---|---|
| Physical Functioning | −0.5; 95% CI: −3.1, 2.0; p = 0.679 | −1.1; 95% CI: −2.6, 0.4; p = 0.15 | −0.2; 95% CI: −1.4, 1.0; p = 0.761 | 0.5; 95% CI: −0.2, 1.2; p = 0.155 | 0.4; 95% CI: −2.6, 3.3; p = 0.815 |
| Role-Physical | −1.2; 95% CI: −5.9, 3.6; p = 0.63 | 2.1; 95% CI: −0.6, 4.8; p = 0.122 | 2.3; 95% CI: 0.0, 4.5; p = 0.049 | 1.4; 95% CI: 0.2, 2.6; p = 0.025 | 6.4; 95% CI: 1.1, 11.8; p = 0.019 |
| Bodily Pain | −2.0; 95% CI: −5.5, 1.4; p = 0.249 | 1.2; 95% CI: −0.8, 3.2; p = 0.221 | 0.4; 95% CI: −1.3, 2.1; p = 0.64 | 0.3; 95% CI: −0.6, 1.2; p = 0.473 | −1.1; 95% CI: −5.2, 3.0; p = 0.609 |
| General Health | −1.0; 95% CI: −4.2, 2.3; p = 0.564 | −0.3; 95% CI: −2.2, 1.6; p = 0.76 | −0.1; 95% CI: −1.6, 1.5; p = 0.948 | 0.7; 95% CI: −0.1, 1.6; p = 0.096 | 1.0; 95% CI: −2.9, 4.8; p = 0.626 |
| Vitality | 1.0; 95% CI: −2.4, 4.4; p = 0.553 | 1.3; 95% CI: −0.7, 3.2; p = 0.199 | 1.0; 95% CI: −0.6, 2.6; p = 0.233 | 0.8; 95% CI: −0.0, 1.7; p = 0.061 | 1.8; 95% CI: −2.2, 5.8; p = 0.379 |
| Social Functioning | 0.5; 95% CI: −3.3, 4.3; p = 0.784 | 1.8; 95% CI: −0.4, 3.9; p = 0.103 | 1.1; 95% CI: −0.7, 2.9; p = 0.234 | 1.1; 95% CI: 0.1, 2.0; p = 0.029 | 4.5; 95% CI: 0.1, 8.9; p = 0.045 |
| Role-Emotional | −2.4; 95% CI: −7.3, 2.4; p = 0.323 | 0.6; 95% CI: −2.2, 3.3; p = 0.688 | 1.1; 95% CI: −1.2, 3.4; p = 0.358 | 1.2; 95% CI: −0.0, 2.5; p = 0.053 | 5.8; 95% CI: 0.1, 11.4; p = 0.045 |
| Mental Health | −0.2; 95% CI: −3.4, 3.1; p = 0.928 | −1.2; 95% CI: −3.1, 0.7; p = 0.216 | 0.2; 95% CI: −1.4, 1.9; p = 0.759 | 0.3; 95% CI: −0.6, 1.2; p = 0.517 | −0.9; 95% CI: −4.9, 3.1; p = 0.66 |
| Physical Component Summary | −0.7; 95% CI: −3.8, 2.4; p = 0.653 | 1.4; 95% CI: −0.3, 3.2; p = 0.114 | 1.0; 95% CI: −0.5, 2.5; p = 0.186 | 0.6; 95% CI: −0.2, 1.4; p = 0.148 | 1.5; 95% CI: −2.2, 5.2; p = 0.415 |
| Mental Component Summary | −0.8; 95% CI: −4.6, 3.1; p = 0.701 | 0.4; 95% CI: −1.9, 2.6; p = 0.751 | 0.9; 95% CI: −0.9, 2.8; p = 0.323 | 0.9; 95% CI: −0.1, 2.0; p = 0.076 | 4.7; 95% CI: 0.1, 9.2; p = 0.044 |
Bold values indicate statistically significant associations (p < 0.05).