TABLE 4.
Multivariate Cox regression analysis of OS and PFS in the Bev+PP group.
| Category | OS | PFS | ||
|---|---|---|---|---|
| HR | p-value | HR | p-value | |
| Gender = female | 0.18 [0.04–0.87] | 0.032* | 0.25 [0.07–0.90] | 0.034* |
| Age (years) | 1.00 [0.95–1.06] | 0.899 | 0.99 [0.95–1.04] | 0.796 |
| Smoking | 0.81 [0.23–2.77] | 0.731 | 0.85 [0.28–2.64] | 0.784 |
| Distant metastasis | 0.95 [0.09–9.83] | 0.65 | 0.82 [0.08–8.33] | 0.65 |
| Lung metastasis | 2.23 [0.79–6.27] | 0.130 | 1.57 [0.65–3.82] | 0.318 |
| Pleura metastasis | 0.51 [0.17–1.58] | 0.245 | 0.58 [0.22–1.54] | 0.273 |
| Adrenal metastasis | 2.18 [0.70–6.82] | 0.179 | 10.17 [2.99–34.62] | 0.000* |
| Bone metastasis | 0.90 [0.36–2.25] | 0.813 | 0.77 [0.33–1.81] | 0.551 |
| Brain metastasis | 0.62 [0.24–1.62] | 0.329 | 1.50 [0.59–3.85] | 0.395 |
| Liver metastasis | 4.34 [0.99–18.91] | 0.051 | 3.04 [0.88–10.58] | 0.080 |
| ECOG ≥ 2 | 1.10 [0.16–7.49] | 0.919 | 2.27 [0.33–15.39] | 0.402 |
| EGFR mutation | 1.08 [0.33–3.56] | 0.899 | 1.28 [0.43–3.78] | 0.660 |
| ALK/ROS1 fusion | 0.00 [0.00-NA] | 0.984 | 0.69 [0.09–5.38] | 0.720 |
| Unknown status | 0.28 [0.06–1.25] | 0.095 | 0.34 [0.09–1.32] | 0.118 |