TABLE 5.

The alignment scores computed for the PDB sequence 3UON against 3NY8 using a miss and gap score of −2.

Target protein	Reference protein	8DP BLOSUM min:−0.84 max: 0.73	8DP GPCRtm min:−0.83 max: 0.75	10DP BLOSUM min:−0.77 max: 0.66	10P GPCRtm min: −0.97 max: 0.66
ACM2/QNB (PDB ID: 3UON)	ADRB2/JRZ (PDB ID: 3NY8)	0.61	0.62	0.59	0.54
ADRB2/JRZ (PDB ID: 3NY8)	ACM2/QNB (PDB ID: 3UON)	0.47	0.49	0.43	0.42

The highest and lowest values for each profiling scoring function obtained by aligning all the diverse GPCRs available in the PDB databank are also reported.