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. 2021 May 7;12:659339. doi: 10.3389/fimmu.2021.659339

Figure 2.

Figure 2

Illustrative summary of events involving estrogen in COVID-19. The initial SARS-CoV-2 viral entry and recruitment of innate and adaptive immune cells culminate in a pathological state following viral infection or successful control of infection. Sex discrepancies could be pertinent due to estrogen hormone that operates at different points as indicated.