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. 2021 May 7;12:605766. doi: 10.3389/fimmu.2021.605766

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Copyright © 2021 Zhao, Liu, Sun, Zhang, Zhou, Wei, Xiong, Cao, Lu, Yang, Zhang, Lu and Lu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cumulative incidences of Grade II-IV and Grade III-IV acute GVHD. (A) Cumulative incidences of Grade II-IV acute GVHD: CAR-T group: 48.1% (95% CI:46.1, 50.1%) vs. chemotherapy group: 25.6% (95% CI: 25.2, 26.0%); p=0.016. (B) Cumulative incidences of Grade III-IV acute GVHD: CAR T-cell group: 11.1% (95% CI: 10.3, 11.9%) vs. chemotherapy group: 11.5% (95% CI: 11.3, 11.7%); p=0.945. (C) Cumulative incidences of Grade II-IV acute GVHD: CRS Grade 0-I 47.4% (95% CI: 44.7, 50.1%) vs. CRS Grade II-IV: 50.0% (95% CI:42.6, 57.4%); p=0.95. (D) Cumulative incidences of Grade III-IV aGVHD: CRS Grade 0-I: 10.5% (95% CI: 9.5, 11.5%) vs. CRS Grade II-IV: 12.5% (95% CI: 9.4, 15.6%); p=0.92.