Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 May 7;12:605766. doi: 10.3389/fimmu.2021.605766

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Zhao, Liu, Sun, Zhang, Zhou, Wei, Xiong, Cao, Lu, Yang, Zhang, Lu and Lu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

LFS and OS. (A) LFS and OS in the CAR-T and chemotherapy groups. The 4-year LFS for the CAR-T group was 70.2% (95% CI:53.0, 87.4%) vs. 64.1% (95% CI:53.5, 74.7%) for the chemotherapy group (p=0.63). The 4-year OS for the CAR-T group was 70.2% (95% CI:53.0, 87.4%) vs. 65.4% (95% CI:54.8, 76.0%) for the chemotherapy group (p=0.681) (B) LFS and OS according to MRD. The 4-year LFS for patients who achieved MRD- CR was 72.2% (95% CI:61.8, 82.6%) and 51.5% (95% CI:34.4, 68.6%) for those that had an MRD+ CR (p=0.024). The 4-year OS for the MRD- CR group was 73.6% (95% CI:63.4, 83.8%) and 51.5% (95% CI:34.4, 68.6%) for the MRD+CR group (p=0.02). (C) LFS and OS according to cGVHD. 4-year LFS for patients without cGVHD was 62.2% (95% CI:46.5, 77.9%), 85.6% (95% CI:75.8,95.4%) for those with limited cGVHD and 36.4% (95% CI:8.0, 64.8%) for those with extensive cGVHD (no vs. limited cGVHD, p=0.009; limited vs. extensive cGVHD, p<0.001; no vs. extensive cGVHD, p=0.20). 4-year OS for the no cGVHD group was 64.9% (95% CI:49.6, 80.2%), 85.6% for the limited cGVHD group (95% CI:75.8, 95.4%) and 36.4% for the extensive cGVHD group (95% CI:8.0, 64.8%) (no vs. limited cGVHD, p=0.019; limited vs. extensive cGVHD, p<0.001; no vs. extensive cGVHD, p=0.123).