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. 2021 May 7;12:669146. doi: 10.3389/fphar.2021.669146

FIGURE 3.

FIGURE 3

Effects of miR-327 on the FGF10/Akt/Nrf2 signaling pathway in H/R H9c2 cells. FGF10 mRNA and protein levels were measured by the qRT-PCR and the Western blot (A-B). FGF10 downstream protein p-PI3K and t-PI3K, p-Akt and t-Akt, antioxidant-related protein nucleus Nrf2 and HO-1, apoptosis-related protein Bax, Bcl-2, Cyt-c, cleaved caspase-9, and cleaved caspase-3 were detected by Western blot analysis in different groups of H9c2 cells (C). Data are expressed as the mean ± SD (n = 3); #p < 0.05 versus the Control group; *p < 0.05 versus the Ad-NC group.