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. 2021 May 7;12:669146. doi: 10.3389/fphar.2021.669146

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Copyright © 2021 Zheng, Yang, Zhang, Yang, Fan, Li, Zhai, Liu and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of downregulation of miR-327 on apoptosis in TBHP treated H9c2 cells. The AV-APC/PI double-staining assay was performed to detect apoptosis in H9c2 cells after TBHP treatment (A-D), and the relative apoptotic indexes in each group were expressed in bar graphs (E). Apoptosis-related protein Bax, Bcl-2, Cyt-c, cleaved caspase-9, and cleaved caspase-3 expression levels were detected by the Western blot analysis in H9c2 cells (F). Data are expressed as the mean ± SD (n = 3); #p < 0.05 versus the Control group; *p < 0.05 versus the Ad-NC group.