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. 2021 May 7;12:669146. doi: 10.3389/fphar.2021.669146

FIGURE 7.

FIGURE 7

Effects of downregulation of miR-327 on the FGF10/Akt/Nrf2 signaling pathway in TBHP-treated H9c2 cells. FGF10 mRNA and protein levels were detected by qRT-PCR and Western blot analysis after TBHP treatment (A, B). Downstream protein p-PI3K and t-PI3K, t-Akt and p-Akt, antioxidant-related protein nucleus Nrf2, and HO-1 were measured by the Western blot analysis in H9c2 cells (C). Data are expressed as the mean ± SD (n = 3); #p < 0.05 versus the Control group; *p < 0.05 versus the Ad-NC group.