Table 1.

Level of evidence and degrees of recommendations.

Level	Type of Evidence	No of Articles	Degrees of Recommendations
1a	Meta analyses, systematic reviews of randomized controlled trails	10	Strongly recommended and directly applicable
1 b	Systematic review of non-randomized controlled trails	6	Highly recommended and directly applicable
1c	Randomized Controlled Trails (RCTs)	8	Recommended and applicable
2a	Evidence based Guidelines	3	Extrapolated evidence from other studies
3a	Non analytic studies such as Cohort, Surveys, case reports and case series	17	Extrapolated Evidence from other studies

Good clinical practice, GCP, WHO, 2011.