Table 3.
The characteristics of included patients
| Authors | Age | Male (%) | Fluid in 24h (ml) | Vasopressors | Mechanical ventilation | P/F ratio | PEEP (cmH2O) |
Plateau pressure (cmH2O) | Compliance (mL/cmH2O) |
LV function | SAPS II | Causes of ARDS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Osman/2009 | ||||||||||||
| RV INJURY (+) | 64 (13) | 35.7% (5/14) | 78.6% (11/14) | 100% (14/14) | 115 (26) | 6 (4) | 28 (6) | 23 (5) |
SVI: 23 (3) (mL/m2) |
55 (25) |
Extra-pulmonary ARDS (1/14) Other etiologies were not reported |
|
| RV INJURY () | 60 (16) | 70.2% (92/131) | 76.3% (100/131) | 100% (131/131) | 98 (35) | 7 (4) | 25 (6) | 32 (10) |
SVI: 36 (12) (mL/m2) |
50 (19) |
Extra-pulmonary ARDS (29/131) Other etiologies were not reported |
|
| Bull/2010 | ||||||||||||
| RV INJURY (+) | 50 | 55.2% (262/475) |
36.4% (173/475) |
100% (44/44) | 160 | 9.3 | 26.2 |
Survived: CI: 4.5 (1.4) Died: CI; 4.4 (1.6) |
APACHE III: 94.3 | Not reported | ||
| RV INJURY () | 100% (323/323) | |||||||||||
| Fichet/2012 | ||||||||||||
| RV INJURY (+) | 60 (4272) | 67.9% (19/28) |
4000 (30006000) |
53% (8/15) | 100% (28/28) |
100 (82117) |
10 (811) |
28 (2630) |
49.5 (3662) | 50 (3855) |
Pneumonia (21/50) Non-pulmonary sepsis (8/50) Aspiration pneumonia (3/50) Other shock (4/50) Drug-induced ARDS (3/50) Others (11/50) |
|
| RV INJURY () | 51 (3765) | 50.0% (9/18) |
4000 (20006000) |
45% (16/35) | 100% (18/18) |
122 (86150) |
8 (810) |
24 (2028) |
63 (5566) | 46 (3562) | ||
| Legras/2015 | ||||||||||||
| RV INJURY (+) | 56 (15) | 50.0% (18/36) * | 100% (36/36) * |
112 (91=154) |
10 (814) ** |
CI: 2.9 (2.63.4) ** (L/min/m2) |
46 (17) |
Pneumonia (62%) No other etiologies were reported |
||||
| RV INJURY () | 47.7% (62/130) * | 100% (130/130) * |
114 (72145) |
11 (812) ** |
CI: 3.2 (2.64.0) ** (L/min/m2) |
|||||||
| Lazzeri/2016 | ||||||||||||
| RV INJURY (+) | 57 (14) | 70.6% (12/17) | 64.7% (11/17) | 100% (17/17) | 44 (19) |
H1N1 influenza (23/74) H3N2 (2/74) Viral pneumonia (8/74) Bacterial pneumonia (43/74) *** |
||||||
| RV INJURY () | 50 (15) | 73.7% (42/57) | 45.6% (26/57) | 100% (57/57) | ||||||||
| Mekontso Dessap /2016 | ||||||||||||
| RV INJURY (+) | 57 (16) | 63.4% (104/164) | 68.,9% (113/164) | 100% (164/164) | 106 (40) | 8 (4) | 26 (5) | 28 (11) | 50 (19) |
Pneumonia (93/164) Aspiration pneumonitis (16/164) Non-pulmonary sepsis (34/164) Others (17/164) |
||
| RV INJURY () | 58 (17) | 68.5% (403/588) | 66.2% (389/588) | 100% (588/588) | 118 (42) | 8 (4) | 24 (4) | 32 (12) | 54 (21) |
Pneumonia (200/588) Aspiration pneumonitis (75/588) Non-pulmonary sepsis (228/588) Others (73/588) |
||
| See/2017 | ||||||||||||
| RV INJURY (+) | 65 (13) | 65.2% (43/66) | 33.3% (22/66) | 89.4% (59/66) | 169 (63) | 7 (3) | 21 (5) | 34 (18) | LVEF<40% (10/66) | APACHE II: 27 (9) |
Pneumonia (57/66) Non-pulmonary sepsis (9/66) |
|
| RV INJURY () | 62 (15) | 61.3% (103/168) | 32.7% (55/168) | 88.1% (148/168) | 172 (69) | 6 (3) | 21 (2) | 29 (12) | LVEF<40% (28/168) | APACHE II: 27 (8) |
Pneumonia (151/168) Non-pulmonary sepsis (17/168) |
|
| Bonizzoli/2018 | ||||||||||||
| RV INJURY (+) | 58 | 53.3% (16/30) | 100% (3/3) | 107 | 12.7 | 54.9% | 43.2 |
Viral pneumonia (7/30) Bacterial pneumonia (23/30) |
||||
| RV INJURY () | 100% (25/25) | |||||||||||
| Zeiton/2018 | ||||||||||||
| RV INJURY (+) | 39 (14) | 30.0% (3/10) | 100% (10/10) | 100% (10/10) | 77 (13) | 14 (1) | 40 (7) |
Pneumonia (9/10) Other causes of ARDS were unclear |
||||
| RV INJURY () | 49 (15) | 48.6% (17/35) | 74.3% (26/35) | 100% (35/35) | 151 (61) | 11 (2) | 32 (10) |
Pneumonia (17/35) Other causes of ARDS were unclear |
RV injury includes RV dysfunction, RV dysfunction with hemodynamic compromise, RV failure, or acute cor-pulmonale in the studies
*The numbers were described for patients with only ACP or without ACP and PFO (Patients with only PFO or with PFO and ACP were excluded)
**The value was reported as median with interquartile range
***The summation of each number did not fit the reported total number
The standard deviation could not be calculated
The numbers and percentages are per total population included in the study but not all patients were evaluated for RVD/ACP. Therefore, the total numbers were different from actually analyzed number of patients