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. 2021 May 7;11:682088. doi: 10.3389/fonc.2021.682088

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Copyright © 2021 Wichmann, Willner, Kuhnt, Kluge, Gradistanac, Wald, Fest, Lordick, Dietz, Wiegand and Zebralla

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Forest plots for hazard ratio (HR) and 2-sided 95% confidence interval (95% CI) from multivariate Cox proportional hazard models for various outcome measures and survival of neck squamous cell carcinoma of unknown primary (NSCCUP) patients built using the stepwise forward likelihood ratio method. Events represents the numbers of events found for the individual predictor and (%) the percentage of patients experiencing the event among those with the characteristic, and HR, 2-sided 95% CI, and 2-sided P value* the outcome attributable to this characteristic according to the final model for the particular measure. P values^# are 2-sided P values from internal validation using bootstrapping applying 1,000 iterations. P values of independent predictors < 0.05 are in bold.