Table 3.
Various survival measures for 5-years outcome of neck squamous cell carcinoma of unknown primary (NSCCUP) patients of cohorts 1 and 2.
| 5 years survival rate | Total | Cohort 1 n (%) |
Cohort 2 n (%) |
P value# | |||
|---|---|---|---|---|---|---|---|
| OS | alive | 65 | 24 | (45.3) | 41 | (66.1) | 0.025 |
| dead | 50 | 29 | (54.7) | 21 | (33.9) | ||
| TSS | alive or NCRD | 86 | 37 | (69.8) | 49 | (79.0) | 0.256 |
| CRD | 29 | 16 | (30.2) | 13 | (21.0) | ||
| CRD & NCRD | alive | 65 | 24 | (45.3) | 41 | (66.1) | 0.072 |
| NCRD CRD |
21 | 13 | (24.5) | 8 | (12.9) | ||
| 29 | 16 | (30.2) | 13 | (21.0) | |||
| CRD | alive | 65 | 24 | (45.3) | 41 | (66.1) | 0.098 |
| CRD | 29 | 16 | (30.2) | 13 | (21.0) | ||
| NCRD | alive | 65 | 24 | (45.3) | 41 | (66.1) | 0.044 |
| NCRD | 21 | 13 | (24.5) | 8 | (12.9) | ||
| DFS | no event | 76 | 33 | (62.3) | 43 | (69.4) | 0.423 |
| event | 39 | 20 | (37.7) | 19 | (30.6) | ||
| PFS | no event | 74 | 32 | (60.4) | 42 | (67.7) | 0.411 |
| event | 41 | 21 | (39.6) | 20 | (32.3) | ||
| Primary | no event | 107 | 47 | (88.7) | 60 | (96.8) | 0.089 |
| detected | event | 8 | 6 | (11.3) | 2 | (3.2) | |
| Nodal control | no event | 105 | 50 | (94.3) | 55 | (88.7) | 0.285 |
| event | 10 | 3 | (5.7) | 7 | (11.3) | ||
| Distant control | no event | 104 | 51 | (96.2) | 53 | (85.5) | 0.051 |
| event | 11 | 2 | (3.8) | 9 | (14.5) | ||
#P value from Pearson’s Chi-square (χ2) tests; ‡ other summarizes R1, R2 or core biopsies taken prior to R(Ch)T; OS, overall survival; TSS, tumor-specific survival; CRD, cancer related death; NCRD, non-cancer related death/death from other cause; DFS, disease-free survival; PFS, progression-free survival; LC, detection of head and neck squamous cell carcinoma primary; NC, nodal control; and DC, distant control.
P values from Pearson’s Chi-square tests < 0.05 are in bold.