Table 4.
Beta | SEM | Wald | p | Odds ratio | CI 95% | |
---|---|---|---|---|---|---|
Analgesic used (<4 times/⩾4 times per week) | 1.466 | 0.576 | 6.480 | 0.011 | 4.33a | (1.40–13.38) |
Heat pain threshold (HPT) | 0.168 | 0.069 | 5.959 | 0.015 | 1.18a | (1.03–1.36) |
Pittsburgh sleep quality index (PSQI, cutoff-Q25 ⩾ 17) | 0.978 | 0.496 | 3.889 | 0.049 | 2.66b | (1.06–7.03) |
Brain-derived neurotrophic factor (BDNF) ⩾ 58.11(ng/mL) | 1.314 | 0.549 | 5.732 | 0.017 | 3.72b | (1.27–10.91) |
Brazilian Portuguese pain catastrophizing scale ⩾33 | 1.300 | 0.477 | 7.432 | 0.006 | 3.67b | (1.44–9.34) |
Number of psychiatric diagnosis | ||||||
None | 5.827 | 0.054 | ||||
One diagnosis | 1.537 | 0.753 | 4.163 | 0.041 | 4.65c | (1.06–20.36) |
Two or more diagnoses | 1.804 | 0.752 | 5.747 | 0.017 | 6.07c | (1.39–26.54) |
Fibromyalgia impact questionnaire (FIQ) ⩾ 78 | 1.927 | 0.775 | 6.189 | 0.013 | 6.86d | (1.50–31.34) |
FIQ: fibromyalgia impact questionnaire
Hierarchical multiple regression analysis. Cutoff point at quartile (cutoff-Q).
Model 1: First block – age, score on VAS (cutoff ⩾ 7), analgesic use (four or more than 4 days per week), heat pain threshold (HPT), psychotropic medication (antidepressant and anticonvulsants).
Model 2: Second block – model I along with catastrophizing pain (cutoff-Q25 = 33), S100B (cutoff-Q75 = 23.43), BDNF (cutoff-Q75 = 58.11) and PSQI (cutoff-Q25 ⩾ 17).
Model 3: Third block – model II along with depressive symptoms by BDI-II, number of psychiatric diagnoses according to the MINI (major depressive episode with dysthymia, mania-depressive disorder and generalized anxiety disorder).
Model 4: Fourth block – model III along with FIQ (cutoff-Q75 = ⩾78) to assess the impact of symptoms on quality of life.