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. 2021 May 7;9:683607. doi: 10.3389/fped.2021.683607

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Copyright © 2021 Schäfer, Meyer, Kellnar, Warmbrunn, Schuster, Simon, Meyer, Platzer, Hubertus, Seitz, Knorr and Stehr.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Forest plot of Cochran-Mantel-Haenszel test with details of study centers for perforated appendicitis per institution 2020 compared to the combined control period 2018–2019 (OR, odds ratio; CI, confidence interval).