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. 2021 May 7;9:683607. doi: 10.3389/fped.2021.683607

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Copyright © 2021 Schäfer, Meyer, Kellnar, Warmbrunn, Schuster, Simon, Meyer, Platzer, Hubertus, Seitz, Knorr and Stehr.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Perforation rate depending on age groups shows increase of overall perforation rate is solely due to increased perforation rate in younger patients (*Fisher's exact test). (B) Perforation rate depending on sex shows increase of overall perforation rate in boys is significantly higher in 2020 (*Fisher's exact test).