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. 2020 Dec 31;14(2):150–167. doi: 10.15283/ijsc20167

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Copyright © 2021 by the Korean Society for Stem Cell Research

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 2 — MSC-secreted miRNA therapy for musculoskeletal diseases. As shown in the figure above, different miRNAs secreted by MSCs act on target cells show a positive effect on musculoskeletal diseases. As shown in table 2, there are many miRNAs related to musculoskeletal diseases. Further, it was confirmed that one miRNA could target different genes in different cells giving different effects.