Fig. 4.

Schematic diagram of E2-MS-human amnion extracellular matrix (HAECM) scaffold as an intrauterine controlled release system for endometrium regeneration and scanning electron microscopy photograph of E₂-MS (502H), HAECM scaffold and E₂-MS- HAECM scaffold (A). Quantitative PCR analysis of EGF, IGF-1, EGFR, and IGF-1R mRNA levels in Ishikawa cells treated with different preparations after 72 ​h. ∗p ​< ​0.05, ∗∗p ​< ​0.01 vs. control group. Data are presented as the mean ​± ​standard deviation; n ​= ​3 (B). (Reproduced with permission of Ref. [84]).