Figure 3.

Drug-induced colitis. Various histological patterns. (A) Drug crystals and remnants can sometimes be seen in a colonic biopsy. In some cases, such as this one, they are surrounded by a foreign-body reaction (H&E, 20x). (B) Eosinophilic colitis can be caused by drugs. In this picture, numerous eosinophils infiltrate the lamina propria and crypt epithelium, forming microabscesses and sometimes degranulating (H&E, 40x). (C) Prominent apoptotic bodies can be seen in some cases of drug-induced colitis, especially with some laxatives and antineoplastic agents (H&E, 40x).