Table 1.
The details of 62 “P5-binding proteins”
| Gene names | Organism | Protein names |
|---|---|---|
| ACSL1a | Homo sapiens (Human) | Long-chain-fatty-acid--CoA ligase 1 |
| ACTN4 | Homo sapiens (Human) | Actinin alpha 4 isoform 3 |
| AIFM1a | Homo sapiens (Human) | Apoptosis-inducing factor 1, mitochondrial |
| ALDH3A2a | Homo sapiens (Human) | Fatty aldehyde dehydrogenase |
| ATL3 | Homo sapiens (Human) | Atlastin-3 |
| CAND1 | Homo sapiens (Human) | Cullin-associated NEDD8-dissociated protein1 |
| CERS2 | Homo sapiens (Human) | Ceramide synthase 2 |
| CKAP4a | Homo sapiens (Human) | Cytoskeleton-associated protein 4 |
| CPT1Aa | Homo sapiens (Human) | Carnitine palmitoyltransferase 1A |
| DDX21 | Homo sapiens (Human) | Nucleolar RNA helicase 2 |
| DHCR24a | Homo sapiens (Human) | Delta(24)-sterol reductase |
| DHX9 | Homo sapiens (Human) | ATP-dependent RNA helicase A |
| EMDa | Homo sapiens (Human) | Emerin |
| GANAB | Homo sapiens (Human) | Neutral alpha-glucosidase AB |
| ILF3 | Homo sapiens (Human) | Interleukin enhancer-binding factor 3 |
| IMMTa | Homo sapiens (Human) | MICOS complex subunit MIC60 |
| LMNAa | Homo sapiens (Human) | Prelamin-A/C |
| LMNB1 | Homo sapiens (Human) | Lamin-B1 |
| MATR3 | Homo sapiens (Human) | Matrin-3 |
| MYH9 | Homo sapiens (Human) | Myosin-9 |
| NDC1 | Homo sapiens (Human) | Nucleoporin |
| NDUFS1 | Homo sapiens (Human) | NADH-ubiquinone oxidoreductase |
| NOP58 | Homo sapiens (Human) | Nucleolar protein 58 |
| NPEPPS# | Homo sapiens (Human) | Puromycin-sensitive aminopeptidase |
| NUP93 | Homo sapiens (Human) | Nuclear pore complex protein Nup93 |
| PARP1 | Homo sapiens (Human) | Poly [ADP-ribose] polymerase 1 |
| PEBP1 | Homo sapiens (Human) | Phosphatidylethanolamine-binding protein |
| PHBa | Homo sapiens (Human) | Prohibitin |
| RPN1a | Homo sapiens (Human) | Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 1 |
| SURF4a | Homo sapiens (Human) | Surfeit 4 |
| TRAP1 | Homo sapiens (Human) | Heat shock protein 75 kDa, mitochondrial |
| UBA1 | Homo sapiens (Human) | Ubiquitin-like modifier-activating enzyme 1 |
| XRCC6 | Homo sapiens (Human) | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| CPT2a | Homo sapiens (Human) | Carnitine O-palmitoyltransferase 2 |
| SF3B3 | Homo sapiens (Human) | Splicing factor 3B subunit 3 |
| SFPQ | Homo sapiens (Human) | Splicing factor, proline- and glutamine-rich |
| SRPRBa | Homo sapiens (Human) | Signal recognition particle receptor subunit beta |
| TMX1 | Homo sapiens (Human) | Thioredoxin-related transmembrane protein 1 |
| GLUD1 | Mus musculus | Glutamate dehydrogenase 1 |
| P4HB | Mus musculus | Prolyl 4-hydroxylase, beta polypeptide |
| PITRM1 | Mus musculus | Pitrilysin metallepetidase 1 |
| RAB11Aa | Mus musculus | RAS oncogene family |
| CAMK2G | Mus musculus | Calcium/calmodulin-dependent protein kinase |
| H2-D1a | Mus musculus | Histocompatibility 2, D region locus 1 |
| PGRMC2a | Mus musculus | P4 receptor membrane component 2 |
| VDAC1a | Mus musculus | Voltage-dependent anion channel 1 |
| VDAC2a | Mus musculus | Voltage-dependent anion channel 2 |
| VDAC3a | Mus musculus | Voltage-dependent anion channel 3 |
| DNAJC1a | Mus musculus | DnaJ heat shock protein family |
| ATP13A1a | Mus musculus | ATPase type 13A1 |
| CANXa | Mus musculus | Calnexin |
| U2AF | Mus musculus | U2 small nuclear ribonucleoprotein auxiliary factor |
| ECH1 | Mus musculus | Enoyl coenzyme A hydratase 1 |
| VIM | Mus musculus | Vimentin |
| PHB2 | Mus musculus | Prohibitin 2 |
| CLUH | Mus musculus | Clustered mitochondria (cluA/CLU1) homolog |
| NPEPPS# | Mus musculus | Aminopeptidase puromycin sensitive |
| CYP51a | Mus musculus | Cytochrome P450, family 51 |
| ANO10 | Mus musculus | Anoctamin 10 |
| SLC25A20a | Mus musculus | Mitochondrial carnitine/acylcarnitine translocase, member |
| ZMPSTE24a | Mus musculus | Zinc metallopeptidase |
| MTAP | Mus musculus | Methylthioadenosine phosphorylase |
| LSSa | Mus musculus | Lanosterol synthase |
a
Also known to interact with sterol in a different cell type, # present in both human cancer and mouse immune cells. 38 P5 target proteins in LNCaP prostate cell line from Homo sapiens and 25 P5 target proteins from CD8+ immune cell from Mus musculus.