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. 2021 May 20;139(7):743–750. doi: 10.1001/jamaophthalmol.2021.1407

Table 1. Characteristics of the 4 Cohort Studies.

Cohort (start year) Patients, No. Age at inclusion, mean (SD), y No. (%) Total eyes, No. Eyes with follow-up data, No. No. (%; 95% CI)
Female Current smoker Previous smoker Prevalent GA Incident GA
BMES (1992) 26 81.6 (7.4) 19 (73) 3 (12) 9 (35) 44 33 12 (27; 14.1-40.4) 32 (73; 59.6-85.9)
RS cohort 1 (1990) 117 83.4 (6.7) 73 (62.4) 27 (23.1) 39 (33.3)a 163 50 70 (43; 23.6-37.8) 93 (57; 49.5-64.7)
RS cohort 2 (2000) 20 81.0 (7.8) 8 (40) 1 (5) 17 (85) 25 5 7 (28; 4.3-35.7) 18 (72; 4.3-35.7)
RS cohort 3 (2006) 8 78.1 (9.7) 6 (75) 1 (13) 3 (38) 10 0 6 (60; 26.2-87.8) 4 (40; 12.2-73.8)
Total 171 82.6 (7.1) 106 (62.0) 32 (18.7) 68 (39.8)a 242 88 95 (39.3; 33.1-45.4) 147 (60.7; 54.6-66.9)

Abbreviations: BMES, Blue Mountains Eye Study; GA, geographic atrophy; RS, Rotterdam Study.

a

Data for 6 patients missing.