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. 2021 May 20;139(7):743–750. doi: 10.1001/jamaophthalmol.2021.1407

Table 2. Area of Geographic Atrophy (GA) at First Presentation and Annual Enlargement.

Cohort Starting area (95% CI), mm2 Starting area (95% CI), mm2 Mean enlargement (95% CI), mm2 per year Mean enlargement (95% CI), mm2 per year
Prevalent GA Incident GA Prevalent GA Incident GA
BMES 4.53 (2.58 to 6.47) 3.34 (0.41 to 6.27) 4.97 (2.96 to 6.98) 1.28 (0.98 to 1.58) 0.92 (0.48 to 1.35) 1.49 (1.11 to 1.86)
RS cohort 1 3.87 (3.10 to 4.65) 6.01 (4.49 to 7.54) 2.27 (1.71 to 2.82) 1.03 (0.73 to 1.32) 1.13 (0.73 to 1.54) 0.83 (0.45 to 1.21)
RS cohort 2 2.04 (0.64 to 3.44) 4.81 (0.35 to 9.27) 0.96 (0.52 to 1.40) 0.53 (0.22 to 0.84) 0.19 (−0.15 to 0.52) 0.77 (0.60 to 0.94)
RS cohort 3 2.39 (0.11 to 4.67) 3.72 (0.24 to 7.20) 0.39 (−0.04 to 0.82) NAa NAa NAa
Total 3.74 (3.11 to 4.67) 5.44 (4.19 to 6.69) 2.64 (2.05 to 3.24) 1.09 (0.89 to 1.30) 1.03 (0.73 to 1.34) 1.16 (0.90 to 1.43)

Abbreviations: BMES, Blue Mountains Eye Study; NA, not applicable; RS, Rotterdam Study.

a

No follow-up data were available.