Fig. 1.
Next-generation sequencing assists in accurate identification of the AML fusion gene site. A. Schematic diagram showing the fusion site detection by targeted sequencing and whole-genome sequencing. B. Schematic diagram showing the method for verification of the AE fusion site by Sanger sequencing. C. Results of breakpoint tracing in AML1 intron 5 and intron 6 and in ETO intron 1 for 49 patients.