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. 2021 May 14;14(8):101119. doi: 10.1016/j.tranon.2021.101119

Fig. 1.

Fig 1

Next-generation sequencing assists in accurate identification of the AML fusion gene site. A. Schematic diagram showing the fusion site detection by targeted sequencing and whole-genome sequencing. B. Schematic diagram showing the method for verification of the AE fusion site by Sanger sequencing. C. Results of breakpoint tracing in AML1 intron 5 and intron 6 and in ETO intron 1 for 49 patients.