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. Author manuscript; available in PMC: 2021 May 21.
Published in final edited form as: Ann N Y Acad Sci. 2019 Aug 18;1460(1):43–56. doi: 10.1111/nyas.14208

Fig.2. Deletion of PGRN accelerates inflammation in diabetic fracture healing.

Fig.2

(A-D) Real-time PCR assay for transcriptional levels of pro-inflammatory cytokines, including TNFα, IL-1β, COX-2 and NOS-2, in the drill-hole model; n=10. (E) Expression of NOS-2 in WT without diabetes, WT with diabetes, PGRN KO without diabetes and PGRN KO with diabetes in the drill-hole model, assayed by immunoblotting. (F) Quantitative analysis of immunoblotting in (E), assayed by ImageJ program. Student’s t-test analysis was used for the statistical analysis. The values are the mean ±SD . *p < 0.05 vs. control group.