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. 2021 May 13;22(1):526. doi: 10.3892/ol.2021.12787

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Copyright: © Zhuang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Protein expression levels of FCGBP are downregulated in advanced-stage CRC tissues. (A) FCGBP mRNA expression in CRC tissues from different pathological stages in the COAD dataset was analyzed by Gene Expression Profiling Interactive Analysis. (B) The FCGBP protein expression in the different pathological stages of CRC tissues were analyzed in a commercially available TMA containing 93 CRC tissues. The representative images were taken at a magnification ×4 and ×20 and showed in the left panel. Each dot represents 1 tissue; median ± range; *P<0.05, vs. I + II stages. COAD, colon adenocarcinoma; CRC, colorectal cancer; FCGBP, Fc fragment of IgG-binding protein.