Table III.

Correlation analysis between FCGBP expression and associated immune cell markers using TIMER.

	No adjustment		Adjusted by tumor purity
Variables	r-value	P-value	r-value	P-value
CD8+ T cell
CD8A	−0.021	0.492	−0.114	3.25×10−4a
CD8B	0.035	0.248	−0.046	0.146
T cell (general)
CD3D	0.008	0.786	−0.098	0.002a
CD3E	0.001	0.966	−0.11	5.04×10−4a
CD2	−0.015	0.615	−0.122	1.10×10−4a
B cell
CD19	0.007	0.007	−0.085	0.007a
CD79A	−0.02	−0.02	−0.132	2.98×10−5a
CD86	0.163	0.163	0.113	3.42×10−4a
CSF1R	0.484	8.55×10−66	0.462	1.06×10−53a
Tumor-associated macrophage
CCL2	0.045	0.134	−0.027	0.394
CD68	0.117	9.67×10−5	0.072	0.023a
IL10	−0.005	0.881	−0.068	0.033a
M1 macrophage
NOS2	0.121	5.48×10−5	0.113	3.40×10−4a
IRF5	0.11	2.45×10−4	0.076	0.017a
PTGS2	0.141	2.72×10−6	0.077	0.015a
M2 macrophage
CD163	0.121	5.58×10−5	0.069	0.030a
VSIG4	0.3	2.35×10−24	0.266	1.48×10−17a
MS4A4A	0.024	0.421	−0.044	0.162
Neutrophil
CEACAM8	0.045	0.136	0.034	0.285
ITGAM	0.309	9.46×10−26	0.267	1.04×10−17a
CCR7	−0.004	0.885	−0.114	3.03×10−4a
Natural killer cell
KIR2DL1	−0.019	0.552	−0.078	0.014a
KIR2DL3	−0.085	0.005	−0.133	2.78×10−5a
KIR2DL4	−0.137	5.52×10−6	−0.199	2.71×10−10a
KIR3DL1	−0.017	0.563	−0.068	0.031a
KIR3DL2	−0.036	0.227	−0.113	3.65×10−4a
KIR3DL3	−0.022	0.459	−0.068	0.033a
KIR2DS4	−0.053	0.082	−0.086	0.006a
Dendritic cell
HLA-DPB1	0.294	1.42×10−23	0.247	2.82×10−15a
HLA-DQB1	0.207	5.02×10−12	0.136	1.79×10−5a
HLA-DRA	0.214	7.76×10−13	0.154	1.11×10−6a
HLA-DPA1	0.243	4.18×10−16	0.187	2.02×10−9a
CD1C	0.328	4.84×10−29	0.289	1.49×10−20a
NRP1	0.185	5.86×10−10	0.128	5.19×10−5a
ITGAX	0.224	4.97×10−14	0.176	2.49×10−8a
T-helper 1 cell
TBX21	−0.001	0.965	−0.102	0.001a
STAT4	0.031	0.304	−0.067	0.035a
STAT1	−0.122	4.87×10−5	−0.172	5.24×10−8a
IFNG	−0.086	0.004	−0.151	1.66×10−6a
TNF	0.191	1.68×10−10	0.158	5.63×10−7a
T-helper 2 cell
GATA3	0.024	0.423	0.069	0.030a
STAT6	0.251	3.17×10−17	0.218	3.33×10−12a
STAT5A	0.303	9.40×10−25	0.258	1.40×10−16a
IL-13	−0.015	0.624	−0.032	0.312
Follicular helper T cell
BCL6	0.294	2.45×10−23	0.283	1.07×10−19a
IL21	−0.054	0.073	−0.117	2.20×10−4a
T-helper 17 cell
STAT3	0.289	1.42×10−22	0.26	9.10×10−17a
IL17A	−0.002	0.937	−0.044	0.168
Regulatory T cell
FOXP3	−0.059	0.051	−0.141	7.57×10−6a
CCR8	−0.09	0.003	−0.142	7.04×10−6a
STAT5B	0.239	1.04×10−14	0.215	6.91×10−12a
TGFB1	0.288	1.64×10−22	0.239	2.05×10−14a
T cell exhaustion
PDCD1	−0.016	0.590	−0.112	3.98×10−4a
CTLA4	−0.077	0.011	−0.161	3.17×10−7a
LAG3	−0.103	6.32×10−4	−0.151	1.61×10−6a
HAVCR2	0.189	2.61×10−10	0.147	3.35×10−6a
GZMB	−0.122	4.87×10−5	−0.222	1.54×10−12a

^aP<0.05.