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. Author manuscript; available in PMC: 2022 May 11.
Published in final edited form as: J Am Coll Cardiol. 2021 May 11;77(18):2291–2303. doi: 10.1016/j.jacc.2021.03.291

TABLE 4.

Relationship of Natriuretic Peptide, Renin, and Aldosterone Rhythm With Systolic Blood Pressure Rhythm

Acrophase Relationship With Systolic Blood Pressure
Overall Lean Obese

MR-proANP
 Phase difference, radians −0.55 −0.18 −1.27
 Phase difference, h −2.1 −0.7 −4.9
 p value <0.001 0.02 <0.001
BNP
 Phase difference, radians −0.39 −0.23 −0.86
 Phase difference, h −1.5 −0.9 −3.3
 p value <0.001 0.02 <0.001
NT-proBNP
 Phase difference, radians −0.08 −0.30 −0.40
 Phase difference, h −0.3 −1.1 −1.5
 p value 0.23 0.06 0.09
Renin
 Phase difference, radians 3.63 3.62 3.32
 Phase difference, h 13.9 13.8 12.7
 p value 0.03 0.04 0.18
Aldosterone
 Phase difference, radians 4.04 3.5 3.51
 Phase difference, h 15.4 13.4 13.4
 p value <0.001 0.02 0.01
*

Phase difference calculated as: acrophase of SBP – acrophase of analyte.

Abbreviations as in Table 1.