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. Author manuscript; available in PMC: 2021 May 21.
Published in final edited form as: Acc Chem Res. 2021 Feb 5;54(5):1143–1156. doi: 10.1021/acs.accounts.0c00823

Figure 4.

Figure 4.

(A) Characterization of lysine hydroxylase GlbB and selected substrate scope. (B) Nine-step total synthesis of cepafungin I empowered by lysine hydroxylation with GlbB. (C) PSMB5 inhibitory assay results with synthetic analogues of 38.