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Tofacitinib strongly downregulates antiviral peptides but only minimally affects gene expression of antimicrobial peptides. a Keratinocytes were stimulated with tofacitinib (600 nM) or left untreated (control). The cells were harvested after 24 h; RNA was isolated from cell lysates and used for DNA MicroArray. Blue colour indicates upregulated genes, while red colour indicates downregulated genes compared to baseline. b Network analysis focusing on antimicrobial and antiviral genes
